橙皮素-7-O-葡萄糖苷 TN1733

Product Introduction
Bioactivity


英文名: Hesperetin 7-O-glucoside

描述: Hesperetin 7-O-glucoside 是通过 Hesperidin 的酶促转化产生的一种人 HMG-CoA 还原酶抑制剂，具有降压作用，可抑制幽门螺杆菌的生长。

体外活性: Hesperetin 7-O-glucoside (Hes-7-G) was produced by the enzymatic conversion of hesperidin by Aspergillus sojae naringinase due to the removal of the terminal rhamnose.Extracts from orange juice and peel containing the hesperidin were so treated by this enzyme that the hesperidin could also be converted to Hesperetin 7-O-glucoside . The solubility of Hesperetin 7-O-glucoside in 10% ethanol was enhanced 55- and 88-fold over those of hesperidin and hesperetin, respectively, which may make Hesperetin 7-O-glucoside more bioavailable. Hesperetin 7-O-glucoside was 1.7- and 2.4-fold better than hesperidin and hesperetin, respectively, in the inhibition of human intestinal maltase. Hesperetin 7-O-glucoside was more potent by 2- and 4-fold than hesperidin in the inhibition of human HMG-CoA reductase. Additionally, Hesperetin 7-O-glucoside exhibited more effective inhibition of the growth of Helicobacter pylori than hesperetin, while its effectiveness was similar to that of hesperidin.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 27.5 mg/mL (59.21 mM)


关键字: Inhibitor | Hesperetin 7-O-glucoside | enzymatic | Antihypertensive | Hesperetin 7Oglucoside | antibacterial | Hesperetin 7 O glucoside | Bacterial | HMG-CoA Reductase (HMGCR) | inhibit | Hesperidin

相关产品: Fuziline | Kaempferol 3-O-sophoroside | Isoastilbin | APOBEC3G-IN-1 | 2,5-Dihydroxybenzaldehyde | Ceftezole sodium | paulownin | Nevadensin | Vincetoxicoside B | Isoforsythiaside

相关库: Inhibitor Library | Traditional Chinese Medicine Monomer Library | Anti-COVID-19 Traditional Chinese Medicine Compound Library | Lipid Metabolism Compound Library | Anti-Bacterial Compound Library | Flavonoid Natural Product Library | Covalent Inhibitor Library | Anti-Infection Compound Library | Natural Product Library | Anti-infective Natural Product Library

橙皮素-7-O-葡萄糖苷 TN1733信息由TargetMol中国为您提供，如您想了解更多关于橙皮素-7-O-葡萄糖苷 TN1733报价、型号、参数等信息，欢迎来电或留言咨询。

注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途