棉花皮素-8-O-葡萄糖醛酸苷 TN1736
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
10 mg | 55366-56-8 | ¥1,770.00 | 询底价 |
50 mg | 55366-56-8 | ¥4,480.00 | 询底价 |
25 mg | 55366-56-8 | ¥3,130.00 | 询底价 |
100 mg | 55366-56-8 | ¥6,330.00 | 询底价 |
1 mg | 55366-56-8 | ¥473.00 | 询底价 |
5 mg | 55366-56-8 | ¥1,180.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Hibifolin
描述: Hibifolin 是一种黄酮醇糖苷,是潜在的腺苷脱氨酶抑制剂。它可以保护神经元免受 beta-淀粉样蛋白诱导的毒性。
体外活性: the inhibitory activity of a plant flavonoid, hibifolin on ADA is investigated using enzyme kinetic assay and isothermal titration calorimetry.?The inhibitory constant of hibifolin was found to be 49.92μM 3.98 and the mode of binding was reversible.?Isothermal titration calorimetry showed that the compound binds ADA with binding energy of -7.21Kcal/mol.?The in silico modeling and docking studies showed that the bound ligand is stabilized by hydrogen bonds with active site residues of the enzyme.?hibifolin can act as a potential inhibitor of ADA.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 5 mM
关键字: Adenosine Deaminase | Hibifolin | adenosine | anti-proliferative | anti-inflammatory | neurotoxicity | Inhibitor | deaminase | inhibit
相关产品: Cladribine | Erdosteine | 8-Azaadenosine | Pentostatin | 3’-O-Methyladenosine
相关库: Anti-Tumor Natural Product Library | Neurotransmitter Receptor Compound Library | Selected Plant-Sourced Compound Library | Bioactive Compounds Library Max | Human Metabolite Library | Inhibitor Library | Natural Product Library for HTS | Metabolism Compound Library | Flavonoid Natural Product Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途