高圣草酚 TN1740

Product Introduction
Bioactivity


英文名: Homoeriodictyol

描述: Homoeriodictyol 是 Eriocitrin 的代谢物，属于黄酮类。Eriocitrin 是强效抗氧化剂。

体外活性: In contrast to other polyphenols, the flavanon Homoeriodictyol promotes glucose uptake by 29.0 ± 3.83% at a concentration of 100 μM. The glucose uptake stimulating effect was sensitive to phloridzin, but not to phloretin, indicating an involvement of the sodium-coupled glucose transporter SGLT-1, but not of sodium-independent glucose transporters (GLUT). In addition, in contrast to the increased extracellular serotonin levels by stimulation with 500 mM D-(+)-glucose, treatment with 100 μM Homoeriodictyol decreased serotonin release by -48.8 ± 7.57% in Caco-2 cells via a phloridzin-sensitive signaling pathway. Extracellular serotonin levels were also reduced by -57.1 ± 5.43% after application of 0.01 μM Homoeriodictyol to human neural SH-SY5Y cells.

存储条件: store at low temperaturePowder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: Eriocitrin | flavonoid | inhibit | metabolite | Inhibitor | Drug Metabolite | Homoeriodictyol

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相关库: Selected Plant-Sourced Compound Library | Bioactive Compounds Library Max | Natural Product Library for HTS | Flavonoid Natural Product Library | Rare Natural Product Library | Bioactive Compound Library

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