异落新妇苷 TN1772
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
2 mg | 54081-48-0 | ¥1,960.00 | 询底价 |
50 mg | 54081-48-0 | ¥9,870.00 | 询底价 |
1 mL | 54081-48-0 | ¥3,860.00 | 询底价 |
100 mg | 54081-48-0 | ¥13,700.00 | 询底价 |
1 mg | 54081-48-0 | ¥1,320.00 | 询底价 |
25 mg | 54081-48-0 | ¥7,560.00 | 询底价 |
5 mg | 54081-48-0 | ¥3,480.00 | 询底价 |
10 mg | 54081-48-0 | ¥4,960.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Isoastilbin
描述: Isoastilbin 是Rhizoma Smilacis glabrae 和Astragalus membranaceus 中的二氢黄酮醇糖苷。它抑制酪氨酸酶活性,还抑制葡萄糖基转移酶,IC50值为 54.3 μg/mL。它具有神经保护、抗氧化、抗微生物和抗凋亡活性,可研究阿尔茨海默氏病。
体外活性: The crude extracts were assayed for antimicrobial activities against Streptococcus sobrinus and for glucosyltransferase (GTase) inhibition. Fourteen extracts inhibited the growth of S. sobrinus by more than 50% and six extracts inhibited GTase activity by more than 50% at a concentration of 100 μg/ml. Koompassia malaccensis (kempas) extracts showed 90% depression of S. sobrinus growth and 80% inhibition of GTase activity at a concentration of 100 μg/ml. Kempas crude extracts were subjected to column chromatography using Sephadex LH-20 and then preparative high-performance liquid chromatography to isolate four compounds A, B, C, and D. These compounds were identified as taxifolin and the flavanonol rhamnoside isomers neoastilbin, astilbin, and Isoastilbin, respectively, from 1H and 13C nuclear magnetic resonance (NMR) spectra and other two-dimensional NMR techniques (COSY, HMBC, and HMQC). Each compound depressed the growth of S. sobrinus over a concentration range of 9.3242.7 μg/ml and showed GTase inhibitory activity with IC50 values in the range 27.4-57.3 μg/ml[1]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 25 mg/mL (55.51 mM)
关键字: disease | anti-apoptotic | glycoside | Tyrosinase | Bacterial | antimicrobial | Inhibitor | Antioxidation | inhibit | Isoastilbin | dihydroflavonol | neuroprotective | Alzheimer's
相关产品: Isoschaftoside | Niranthin | 8-Epidiosbulbin E acetate | Antibacterial agent 27 | Ceftezole sodium | Baicalin methyl ester | α-Terpineol | Licoflavone B | Sulfabrom | Vincetoxicoside B
相关库: Anti-Neurodegenerative Disease Compound Library | Oxidation-Reduction Compound Library | Inhibitor Library | Traditional Chinese Medicine Monomer Library | Natural Product Library for HTS | Miao medicine Compound Library | Anti-Bacterial Compound Library | Tibetan medicine Compound Library | Natural Product Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途