堪非醇 3-新橙皮糖苷 TN1819
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
5 mg | 32602-81-6 | ¥950.00 | 询底价 |
1 mL | 32602-81-6 | ¥1,520.00 | 询底价 |
1 mg | 32602-81-6 | ¥392.00 | 询底价 |
10 mg | 32602-81-6 | ¥1,380.00 | 询底价 |
25 mg | 32602-81-6 | ¥2,350.00 | 询底价 |
50 mg | 32602-81-6 | ¥3,490.00 | 询底价 |
100 mg | 32602-81-6 | ¥4,970.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Kaempferol 3-neohesperidoside
描述: Kaempferol 3-neohesperidoside (Kaempferol 3-O-neohesperidoside) 是一种类黄酮,对大鼠比目鱼肌具有拟胰岛素作用。
体外活性: A stimulatory effect of Kaempferol 3-neohesperidoside ( 1) on glucose uptake (35% and 21%) was observed when the rat soleus muscle was incubated with 1 and 100 nM of this flavonoid glycoside, respectively. The concentration-response curve of insulin showed a stimulatory effect at 3.5 and 7.0 nM (42% and 50%) on glucose uptake when compared with the control group. The effect of Kaempferol 3-neohesperidoside on glucose uptake was completely nullified by pretreatment with LY294002, an inhibitor of phosphoinositide 3-kinase (PI3K), and RO318220, an inhibitor of protein kinase C (PKC). However, no significant change occurred on glucose uptake stimulated by Kaempferol 3-neohesperidoside when muscles were pretreated with PD98059, an inhibitor of mitogen-activated protein kinase (MEK), and cycloheximide, an inhibitor of protein synthesis. Kaempferol 3-neohesperidoside and insulin (7 nM) did not show a synergistic effect on glucose uptake. Additionally, 100 mg/kg of Kaempferol 3-neohesperidoside by oral gavage was able to increase glycogen content in the muscle[1]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 55 mg/ml (92.51 mM)
关键字: inhibit | Kaempferol 3-neohesperidoside | Inhibitor | Kaempferol 3neohesperidoside | Kaempferol 3 neohesperidoside
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途