氯化锦葵色素-3-O-半乳糖苷 TN1908

Product Introduction
Bioactivity


英文名: Malvidin-3-galactoside chloride

描述: Malvidin-3-O-galactoside chloride has antioxidant activity.

体外活性: The hepato-cellular accumulation of widely used drugs such as statins and some anticancer drugs is mediated by the liver-specific OATP1B1 and OATP1B3, thus any interference with expression of these particular transporters might influence therapeutic outcomes. We evaluated the effects of 21 anthocyanins and their corresponding 6 anthocyanidins on the expression levels of SLCO1B1/SLCO1B3 by RT-qPCR. Changes in OATP protein levels were confirmed by western blotting. Our data show that OATP1B1 responds differently to anthocyans compared with OATP1B3. We observed the induction of SLCO1B1 gene and OATP1B1 protein in four hepatocyte samples by the anthocyanins malvin chloride, Malvidin-3-O-galactoside chloride and cyanidin-3-O-sophoroside chloride. For SLCO1B3, a reduction in the expression levels was seen with delphin chloride and the anthocyanidin pelargonidin. Although the values varied considerably between primary hepatocyte isolates from different individuals, a mean induction of SLCO1B1 (up to 60%) and reduction of SLCO1B3 (by less than 25%) were detected.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: Malvidin-3-O-galactoside Chloride | Malvidin3galactoside chloride | Malvidin-3-galactoside Chloride | Malvidin 3 galactoside chloride

氯化锦葵色素-3-O-半乳糖苷 TN1908信息由TargetMol中国为您提供，如您想了解更多关于氯化锦葵色素-3-O-半乳糖苷 TN1908报价、型号、参数等信息，欢迎来电或留言咨询。

注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途