通光藤甙元乙 TN2263

Product Introduction
Bioactivity


英文名: Tenacigenin B

描述: Tenacigenin B是一种天然产物，属于萝藦科牛奶菜属，其产品编号为 TN2263，CAS号为 80508-42-5。Tenacigenin B可用作对照参考。

体外活性: Tenacissimoside A (1) and 11alpha-O-benzoyl-12beta- O-acetylTenacigenin B (2), two derivatives of Tenacigenin B (3) from the plant Marsdenia tenacissima, reversed multidrug resistance in P-glycoprotein (Pgp)-overexpressing multidrug-resistant cancer cells. The sensitivity of HepG2/Dox cells to the antitumor drugs doxorubicin, vinblastine, puromycin, and paclitexel was increased by 18-, 10-, 11-, and 6-fold by 20 microg/mL (or 25 microM) of 1 and 16-, 53-, 16-, and 326-fold by 20 microg/mL (or 39 microM) of 2, respectively[1]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: Tenacigenin B

相关产品: Lappaol F | Agnuside | Valspodar | AZD-5672 | Bacoside A3 | Verapamil hydrochloride | ent-16alpha,17-Dihydroxyatisan-3-one | Laniquidar TFA | Larotaxel | Trifluoperazine

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途