黄芪紫檀烷苷 TN2354

Product Introduction
Bioactivity


英文名: Methylnissolin

描述: Methylnissolin (3-Hydroxy-9,10-dimethoxyptercarpan) 是从黄芪中分离的一种天然产物，可抑制血小板衍生生长因子(PDGF)-BB 诱导的细胞增殖，IC50为 10 μM。。它通过抑制 ERK1/2MAP 激酶级联反应抑制 PDGF-BB 诱导的血管平滑肌细胞增殖。它还抑制 PDGF-BB 诱导的细胞外信号调节激酶 1/2 (ERIC1/2) 丝裂原活化蛋白 (MAP) 激酶的磷酸化，具有抗菌和抗癌作用。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 25 mg/mL (83.25 mM)


关键字: Astrapterocarpan | ERK | Inhibitor | Platelet-derived growth factor receptor | Extracellular signal regulated kinases | Methylnissolin | inhibit | PDGFR

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相关库: Chinese Pharmacopoeia Natural Product Library | Anti-Obesity Compound Library | Tyrosine Kinase Inhibitor Library | Traditional Chinese Medicine Monomer Library | Natural Product Library for HTS | Anti-COVID-19 Traditional Chinese Medicine Compound Library | Food as Medicine Compound Library | Tibetan medicine Compound Library | RO5 Drug-like Natural Product Library | Traditional Mongolian Medicine Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途