5-羟基色胺 TN2437

Product Introduction
Bioactivity


英文名: Serotonin

描述: Serotonin (5-hydroxytryptamine) 是 CNS 中的单胺神经递质和内源性5-HT 受体激动剂。它也是儿茶酚 O-甲基转移酶(COMT) 的抑制剂，Ki 值为 44 μM。

体外活性: 在棕色脂肪细胞分化初期，需要时钟表达，而血清素通过调节时钟功能干扰了这一过程。血清素通过降低活性形式的钙/钙调蛋白依赖性蛋白激酶II型γ亚单位的水平，干扰时钟功能。

存储条件: store at low temperature,keep away from moisture,keep away from direct sunlightPowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 55 mg/ml (312.11 mM)


关键字: Inhibitor | Endogenous Metabolite | Serotonin | 5-hydroxytryptamine Receptor | inhibit | Serotonin Receptor | COMT | 5-HT Receptor

相关产品: pCPA methyl ester hydrochloride | Pirenperone | WAY-607695 | A-582941 dihydrochloride | Cinanserin hydrochloride | Buspirone | Pheniramine maleate | Iferanserin | Cariprazine hydrochloride | Nemifitide diTFA

相关库: Human Endogenous Metabolite Library | Anti-Neurodegenerative Disease Compound Library | Tobacco Monomer Library | Membrane Protein-targeted Compound Library | Inhibitor Library | GPCR Compound Library | Human Endogenous Metabolite Compound Library Plus | Traditional Chinese Medicine Monomer Library | Natural Product Library for HTS | RO5 Drug-like Natural Product Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途