盐酸赛洛唑啉 T0042

Product Introduction
Bioactivity


英文名: Xylometazoline hydrochloride

描述: Xylometazoline hydrochloride (Xylometazoline HCl) 是一种 α- 肾上腺素受体激动剂，是一种鼻血管收缩药。

体外活性: Xylometazoline 是一种常用的鼻腔血管收缩剂，可作为 α-肾上腺素能受体激动剂，并在α2B-肾上腺素能受体上表现出较高的活性（EC50 ：99 μM）。Xylometazoline 对α1A、α1B、α1D、α2A、α2B以及α2C肾上腺素能受体的 IC50值分别为 0.08、0.56、0.45、0.98、1.8、0.22 μM。[1]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 26 mg/mL (92.6 mM)
Ethanol : 52 mg/mL (185.2 mM)
H2O : 51 mg/mL (181.6 mM)


关键字: Adrenergic Receptor | increase nasal airflow | constrict nasal blood vessels | nose stuffiness | Inhibitor | Xylometazoline hydrochloride | Xylometazoline Hydrochloride | Beta Receptor | inhibit | Xylometazoline | runny nose

相关产品: Promethazine | Thioridazine hydrochloride | Bedoradrine sulfate | Doxazosin | nifenalol.HCl | Metaproterenol hemisulfate | Mapenterol hydrochloride | Midodrine | Pimozide | Clonidine

相关库: Anti-Neurodegenerative Disease Compound Library | Drug Repurposing Compound Library | Anti-Cancer Compound Library | Anti-Cancer Drug Library | Clinical Compound Library | Membrane Protein-targeted Compound Library | Neuronal Signaling Compound Library | GPCR Compound Library | Anti-Cancer Clinical Compound Library | Anti-Cancer Approved Drug Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途