异炔诺酮 T0171

Product Introduction
Bioactivity


英文名: Norethynodrel

描述: Norethynodrel (Lynestrol) 是一种合成的孕激素，其作用和用途类似于孕酮。它已被用于治疗功能性子宫出血和子宫内膜异位症。它作为避孕药，通常与 MESTRANOL 联合使用。

激酶实验: Assay of glutamate released: Hippocampal slices (400 μM) are prepared from the guinea pig brain using standard techniques. A slice is fixed on a pair of silver wire electrodes (10 Hz, 5 V, 0.1 ms in duration) at 1-minutes intervals for 10 minutes and submerged in 1 mL standard artificial cerebrospinal fluid (ACSF) (in mM: 125 mM NaCl, 5 mM KCl, 1.24 mM KH2PO4, 1.3 mM MgSO4, 2 mM CaCl2, 26 mM NaHCO3, and 10 mM glucose) oxygenated with 95% O2 and 5% CO2 at 36 °C in the presence and absence of tetrodotoxin (TTX) (0.5 μM). In a different set of experiments, electrical stimulation is applied to slices treated with Nefiracetam (1 μM) in the presence and absence of α-bungarotoxin (50 nM) or mecamylamine (3 μM). A 100 μL aliquot of the medium filtered with millipore filters (0.45 μM) is injected onto the cation-exchanger column of the autoanalyser to separate amino acids and the amount of glutamate released is calculated using known amino acid standard concentrations.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: H2O : 8.95 mg/L


关键字: NSC 15432 | SC-4642 | progestagen | NSC-15432 | inhibit | SC4642 | Enidrel | Endogenous Metabolite | Inhibitor | inhibition of ovulation | NSC15432 | Norethynodrel | SC 4642

相关产品: Nestoron | Natamycin | Progesterone | Fulvestrant | Estradiol | Fluticasone (propionate) | Methylpiperidino pyrazole | STF-62247 | Megestrol acetate | Ulipristal

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途