多拉菌素 T0969

Product Introduction
Bioactivity


英文名: Doramectin

描述: Doramectin (Dectomax) 是 Ivermectin 的衍生物。它是一种抗寄生虫抗生素。它具有在 NMRI 小鼠感染模型中抗曼氏链球菌作用。

激酶实验: To determine which caspases are involved in apoptosis induced by taxol, caspase-3 inhibitor (DEVD-CHO), caspase-6 inhibitor (Z-VEID-FMK), caspase-8 inhibitor (Z-IETD-FMK or IETD-CHO), caspase-9 inhibitors (Z-LEHD-FMK or LEHD-CHO), and caspase-10 inhibitor (Z-AEVD-FMK) are used. These caspase inhibitors are dissolved in dimethyl sulfoxide (Me2SO); the final concentration of Me2SO is 0.1%. Cells (5×105) are preincubated in the presence or absence of 100 μM?each of these inhibitors for 3 h at 37°C then treated with or without 0.1, 0.5, and 1 μM?Paclitaxel for 48 h and processed for annexin V binding assay.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 30 mg/mL (33.37 mM)


关键字: Doramectin | Parasite | Antibiotic | Inhibitor | inhibit

相关产品: Nifursol | Daptomycin | Nisin | Doxycycline (hyclate) | Bestatin | Avermectin B1 | Danofloxacin mesylate | Leucomycin | Cefonicid sodium | Sulfacetamide

相关库: Antibiotics Library | FDA-Approved & Pharmacopeia Drug Library | Bioactive Compounds Library Max | Macrocyclic Compound Library | Anti-Parasitic Compound Library | Antiparasitic Natural Product Library | Microbial Natural Product Library | NO PAINS Compound Library | Anti-Infection Compound Library | Natural Product Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途