化合物Tuvusertib T10406

Product Introduction
Bioactivity


英文名: Tuvusertib

描述: Tuvusertib (M1774) 是一种可口服的共济失调毛细血管扩张和 Rad3相关(ATR)激酶抑制剂(Ki< 1 µΜ)，具有选择性和潜在的抗肿瘤活性。Tuvusertib 选择性抑制 ATR 活性，阻断丝氨酸/苏氨酸蛋白激酶检查点激酶1 (CHK1)的下游磷酸化，从而抑制 DNA 损伤检查点激活，破坏 DNA 损伤修复，诱导肿瘤细胞凋亡。

存储条件: store at low temperature,keep away from direct sunlightPowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 6.25 mg/mL (16.88 mM)


关键字: Tuvusertib | M 1774 | M-1774

相关产品: Lidocaine hydrochloride | BQZ-485 | BIO-acetoxime | SU11274 | 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil | Lexatumumab | Erdafitinib | 10-Gingerol | Ginsenoside Rk1 | Urolithin A

相关库: Drug Repurposing Compound Library | Anti-Cancer Compound Library | Anti-Cancer Drug Library | Clinical Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Anti-Cancer Clinical Compound Library | Kinase Inhibitor Library | Anti-Cancer Active Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途