硫双二氯酚亚砜 T10551

Product Introduction
Bioactivity


英文名: Bithionol sulfoxide

描述: Bithionol sulfoxide is a clinically approved antiparasitic drug with the inhibitory against solid tumor growth in several preclinical cancer models.

体外活性: Bithionol caused dose-dependent cytotoxicity against all ovarian cancer cell lines tested (IC50s: 19 μM - 60 μM). BT treatment resulted in cell cycle arrest at the G1/M phase and increased ROS generation [1]. Both bithionol and bithionol sulphoxide demonstrated in vitro toxicity to Neoparamoeba spp. at all concentrations examined (0.1 to 10 mg/l over 72 h), with comparable toxicity to freshwater observed for both chemicals at concentrations > 5 mg/l following a 72 h treatment [2].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 250 mg/mL (671.95 mM)


关键字: Bithionol sulfoxide

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途