化合物BMT-145027 T10573
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
100 mg | 2018282-44-3 | ¥4,870.00 | 询底价 |
50 mg | 2018282-44-3 | ¥3,730.00 | 询底价 |
25 mg | 2018282-44-3 | ¥2,630.00 | 询底价 |
1 mg | 2018282-44-3 | ¥383.00 | 询底价 |
500 mg | 2018282-44-3 | ¥9,720.00 | 询底价 |
5 mg | 2018282-44-3 | ¥942.00 | 询底价 |
10 mg | 2018282-44-3 | ¥1,590.00 | 询底价 |
Product Introduction
Bioactivity
英文名: BMT-145027
描述: BMT-145027 是一种 mGluR5 的正变构调节剂,没有内在的激动剂活性 (EC50 = 47 nM)。
体外活性: BMT-145027 lacks inherent mGluR5 agonist activity when tested at concentrations up to 16 μM. BMT-145027 exhibits high MsLM stability (85% remaining) and a modest decrease in planarity (Fsp3 = 0.17)[1].
体内活性: BMT-145027 (30 mg/kg) leads to a significant increase in time spent with the novel object, with an apparent trend in novel object preference at 10 mg/kg. Satellite animals(BMT-145027: 30 mg/kg) indicates a total plasma concentration of 2800 nM[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 2 mg/mL (4.56 mM)
关键字: Inhibitor | mGluR | inhibit | BMT-145027 | BMT145027 | BMT 145027 | Metabotropic glutamate receptors
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相关库: Anti-Neurodegenerative Disease Compound Library | Neurotransmitter Receptor Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Neuronal Signaling Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途