蒽林 T1068

Product Introduction
Bioactivity


英文名: Dithranol

描述: Dithranol (cignoline) 是蒽醌衍生物，可破坏线粒体功能和结构，用于治疗皮肤病。

激酶实验: THP-1 and HEK293 cells are transiently transfected using DEAE-dextran and Polyfect reagent, respectively. Plasmids transfected contain genes coding for the NF-κB-dependent pELAM-luc luciferase reporter, TLR2, TLR4, CD14, and MD2. Cells (5×105 THP-1 or 1×105 HEK293) are added to 12-well plates, washed after 18 h, and stimulated for 5 h. Cells are then lysed with reporter lysis buffer as directed, and lysates are analyzed for luminescence using Promega luciferase substrate and a Monolight 3010 luminometer.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: Chloroform : 41 mg/mL
DMSO : 10 mM


关键字: Dithranol | DNA/RNA Synthesis | plaques | repair | replication | psoriatic | DNA | Inhibitor | inhibit

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途