化合物 T10779 T10779
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 104391-26-6 | ¥6,150.00 | 询底价 |
2 mg | 104391-26-6 | ¥1,370.00 | 询底价 |
5 mg | 104391-26-6 | ¥2,320.00 | 询底价 |
50 mg | 104391-26-6 | ¥7,990.00 | 询底价 |
100 mg | 104391-26-6 | ¥13,700.00 | 询底价 |
Product Introduction
Bioactivity
英文名: CGP 25454A
描述: CGP 25454A is a novel and selective antagonist of the presynaptic dopamine autoreceptor.
体外活性: CGP 25454A increases the field-stimulated [3H]- and [14C]-overflow from rat striatal slices preloaded with [3H]dopamine and [14C]choline, indicating that CGP 25454A is able to enhance the release of both dopamine (DA) and acetylcholine (ACh). However, CGP 25454A is 12.9 times more potent in increasing, by 1/6 of the apparent maximal increase, the release of [3H]DA than that of [14C]ACh.
体内活性: CGP 25454A increase [3H]spiperone binding to receptors of the D2 family in rat striatum by 90-110% (ED50: 13 mg/kg i.p.). At 30-100 mg/kg, CGP 25454A inhibits [3H]spiperone binding in the pituitary of the same animals as a result of a blockade of postsynaptic DA receptors.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 3.5 mg/mL (10.11 mM)
关键字: CGP 25454A
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途