化合物 T10835L T10835L

Product Introduction
Bioactivity


英文名: Cletoquine oxalate

描述: Cletoquine oxalate (Desethylhydroxychloroquine oxalate) is a major active metabolite of Hydroxychloroquine. Cletoquine has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune disease treatment.

体内活性: Hydroxychloroquine (5 mg/kg intravenously) is administered to BALB/c mice for blood and tissue to determine the content of Cletoquine. The tissue to blood concentration ratio (Kp) is ≥1, indicating the accumulation of Cletoquine in tissues. The Cletoquine Kp ratios for the various tissues are observed in the descending order of liver (114.3)>kidney (24.4)>spleen (19.3)>lungs (16.5)>heart (5.5) [3].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: Cletoquine Oxalate | Desethylhydroxychloroquine Oxalate | Cletoquine oxalate

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途