化合物ESI-08 T11234

Product Introduction
Bioactivity


英文名: ESI-08

描述: ESI-08 是 EPAC2 的有效拮抗剂，IC50 为 8.4 μM。 ESI-08 特异性阻断 cAMP 诱导的 EPAC 活化，但不阻断 cAMP 介导的 PKA 活化。

体外活性: ESI-08 (25 μM) does not alter cAMP-induced type I and II PKA holoenzymes activation while H89, a selective PKA inhibitor, blocked the type I or II PKA activities completely[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 50 mg/mL (141.45 mM)


关键字: ESI-08 | EPAC2 | cAMP | exchange | proteins | ESI08 | EPAC | Ras | inhibit | EPAC1 | ESI 08 | Inhibitor

相关产品: Eriocalyxin B | KH7 | 7-Methoxyrosmanol | I942 | Dodoviscin A | Methyl orsellinate | CB1R Allosteric modulator 3 | Panaxydol | ESI-05 | Adenosine receptor A1 antagonist 5

相关库: Anti-Cancer Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Inhibitor Library | GPCR Compound Library | Covalent Inhibitor Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途