化合物 T11642 T11642

Product Introduction
Bioactivity


英文名: Imidaprilate

描述: Imidaprilate is an active metabolite of TA-6366, acts as a potent angiotensin-converting enzyme (ACE) inhibitor (IC50: 2.6 nM). It is used in the research of the hypertensive disease.

体外活性: Imidaprilate augments the bradykinin-induced contraction of guinea pig ileum, with AC50 of 1.7 nM.Imidaprilate ?is an active metabolite of 6366, acts as a potent angiotensin converting enzyme (ACE) inhibitor, with an IC50 of 2.6 nM.

体内活性: Imidaprilate (≥0.2 mg/kg) inhibits angiotensin I (AT-I)-induced pressor response.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: Imidaprilate

相关产品: TRV-120027 acetate (1234510-46-3 free base) | Ceronapril | L162389 | Pratosartan | Leucosceptoside A | Rentiapril | Methyl candesartan | Eprosartan Mesylate | C-Type Natriuretic Peptide (CNP) (1-22), human | Moexipril hydrochloride

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途