伊诺加群 T11659

Product Introduction
Bioactivity


英文名: Inogatran

描述: Inogatran is a synthetic thrombin inhibitor, developed for the possible treatment and prophylaxis of venous and arterial thrombotic diseases.

体内活性: Inogatran also improves vena caval blood flow and reduces the overall incidence of thrombotic occlusion in a rat model.Inogatran (H-314-27; 0.075, 0.25, 0.75 mg/kg, i.v.) results in dose-dependent increases in activated partial thromboplastin time (aPTT), thrombin time (TT), and prothrombin time (PT) in a canine electrolytic injury model of venous thrombosis. Inogatran dose-dependently inhibits thrombus formation, which is measured as an increase in time to occlusion (TTO) and a decrease in thrombus weight.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: Inogatran

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途