化合物 T11792 T11792
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 170365-25-0 | ¥10,600.00 | 询底价 |
100 mg | 170365-25-0 | ¥17,500.00 | 询底价 |
50 mg | 170365-25-0 | ¥13,800.00 | 询底价 |
Product Introduction
Bioactivity
英文名: KW-8232 free base
描述: KW-8232 free base can reduces the biosynthesis of PGE2, is an anti-osteoporotic agent.
体外活性: KW-8232 reduces the biosynthesis of PGE2 in mouse osteoblastic cells.KW-8232 free base is an anti-osteoporotic agent.
体内活性: KW-8232 markedly decreases urinary calcium excreation in the neurectomized rats only at 30 mg/kg, and highly reduces urinary pyridinoline and deoxypyridionline excretion which are markers of bone resorption in neurectomized rats. KW-8232 inhibits bone loss may be attributed to the lower prostaglandins (PGs)-stimulated bone resorption via regulation of PGE2 production.KW-8232 (3, 10, 30 mg/kg, p.o.) potently increases the femoral bone mineral density (BMD) of immobilized legs of rats, and affects immobilization-induced abnormal bone turnovrer.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: KW-8232 | KW8232 free base | KW-8232 free base | KW8232 | KW 8232 | KW 8232 free base
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途