化合物 T11859L T11859L
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
100 mg | 910634-41-2 | ¥17,500.00 | 询底价 |
5 mg | 910634-41-2 | ¥2,330.00 | 询底价 |
50 mg | 910634-41-2 | ¥12,500.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Litronesib
描述: Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.
体外活性: Litronesib (LY2523355) is a selective Eg5 inhibitor. Litronesib (25 nM) induces cancer cells to death during mitotic arrest, and this needs sustained activation of spindle-assembly checkpoint (SAC)[1].
体内活性: Litronesib (LY2523355; 1.1, 3.3, 10, and 30 mg/kg, i.v.) displays antitumor activity in a dose-dependently. It also leads to a dramatic increase in cancer cells immuno-positive for histone H3 phosphorylation in Colo205 xenograft tumors[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 50 mg/mL (97.71 mM)
关键字: KF89617 | LY 2523355 | LY2523355 | Litronesib | KF 89617
相关产品: GW406108X | S-trityl-L-Cysteine | Mps1-IN-3 | Empesertib | BOS-172722 | GSK-923295 | Eg5-IN-1 | EMD534085 | MPI-0479605 | UMK57
化合物 T11859L T11859L信息由TargetMol中国为您提供,如您想了解更多关于化合物 T11859L T11859L报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途