化合物 T11875 T11875

Product Introduction
Bioactivity


英文名: LPA2 antagonist 2

描述: LPA2 antagonist 2 is ＞480-fold more selective than LPA3 (IC50 of 13.85 μM).LPA2 antagonist 2 is a selective LPA2 antagonist with an IC50 of 28.3 nM and a Ki of 21.1 nM.

体外活性: Lysophosphatidic acid (LPA) is a phospholipid mediator that elicits a host of biological effects including cell proliferation, survival, motility and differentiation. ?LPA2 antagonist 2 inhibits LPA1 with an Imax of 59.0% at 30 μM[1].?LPA has been shown to regulate cancer cell invasion, metastasis, and resistance to both chemotherapeutics and radiation.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 83.33 mg/mL (219.09 mM)


关键字: LPA2 antagonist 2 | LPA-2 antagonist 2

相关产品: ASP6432 | ONO-7300243 | TAK-615 | TC LPA5 4 | LPA1 receptor antagonist 1 | H2L5186303 | Radioprotectin-1 | GRI977143 | LX-1031 | Ki16198

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途