化合物 T12944 T12944
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 1064662-40-3 | ¥10,600.00 | 询底价 |
100 mg | 1064662-40-3 | ¥17,500.00 | 询底价 |
50 mg | 1064662-40-3 | ¥13,800.00 | 询底价 |
Product Introduction
Bioactivity
英文名: SNT-207707
描述: SNT-207707 is a potent, selective and orally active antagonist of melanocortin MC-4 receptor(IC50 of 8 nM (binding) and 5 nM (function) on the MC-4 receptor).
体外活性: SNT-207707 binds to MC-4 receptor with an affinity of 8 nM, and has over 200-fold selectivity vs. MC-3 and MC-5. SNT207858 is a 22 nM MC-4 antagonist with a 170-fold selectivity vs. MC-3 and a 40-fold selectivity versus MC-5.
体内活性: food intake of the mice distinctly increased by SNT-207707(Single subcutaneous injection of 20 mg/kg). Once daily oral administration of both compounds SNT207858 and SNT-207707 starting the day after tumor implantation significantly reduces the tumor induced weight loss.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 250 mg/mL (454.40 mM)
MEthanol : 250 mg/mL (454.40 mM)
关键字: SNT207707 | SNT 207707 | SNT-207707
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途