化合物 T13056 T13056
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
100 mg | 1597426-52-2 | ¥21,500.00 | 询底价 |
25 mg | 1597426-52-2 | ¥12,800.00 | 询底价 |
50 mg | 1597426-52-2 | ¥16,800.00 | 询底价 |
Product Introduction
Bioactivity
英文名: T-448 free base
描述: T-448 free base is a specific, orally active and irreversible lysine-specific demethylase 1 (LSD1, an H3K4 demethylase) inhibitor(IC50 of 22 nM).
体外活性: The levels of H3K4 methylation enhanced by T-448, and increased mRNA expression of neural plasticity-related genes including brain derived neurotrophic factor (Bdnf), and ameliorated learning dysfunction.
体内活性: T-448 increases brain H3K4 methylation and partially restored learning function in mice with NMDA receptor hypofunction. T-448 increases H3K4 methylation in the brain without causing hematological side effects even at 100 mg/kg.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: T 448 free base | T-448 | T 448 | T448 free base | T-448 free base | T448
相关产品: Eicosapentaenoic Acid | GSK-J1 | JQKD82 | OG-L002 | KDM4C-IN-1 | GSK-J4 | QC6352 | (rel)-Tranylcypromine D5 hydrochloride | LSD1-IN-24 | GSK2879552 2HCl (1401966-69-5(free base))
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途