妥卡尼 T13177L

Product Introduction
Bioactivity


英文名: Tocainide

描述: Tocainide 是口服有活性的 sodium channel 阻滞剂，阻断产生疼痛的病灶中(神经膜上)的钠通道。它是利多卡因 (lignocaine) 的伯胺类似物，可用于研究心律不齐。

体内活性: Ventricular ectopic activity in unanesthetized dogs with coronary occlusion effectively suppressed by Tocainide (100 mg/kg). In both digitalis toxicity and coronary occlusion models, the Termination of tocainide infusion results in the prompt return of ventricular ectopic activity [1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 11 mg/mL (57.21 mM)


关键字: Sodium Channel | Na+ channels | tinnitus | Tocainide | lidocaine | Na channels | Inhibitor | inhibit

相关产品: PF-04885614 | Propafenone | NHE3-IN-1 | MitTx-alpha | Vindorosine | Phenazopyridine hydrochloride | Raxatrigine | Phenytoin sodium | Bupivacaine hydrochloride | Procainamide hydrochloride

相关库: Drug Repurposing Compound Library | ReFRAME Related Library | FDA-Approved & Pharmacopeia Drug Library | Anti-Cancer Drug Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Human Metabolite Library | Anti-Cancer Approved Drug Library | Anti-Cardiovascular Disease Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途