化合物 T13198 T13198

Product Introduction
Bioactivity


英文名: Transcrocetin meglumine salt

描述: Transcrocetin meglumine salt is a natural product isolated from saffron (Crocus sativus L.) and is a high-affinity antagonist of the NMDA receptor.

体外活性: Transcrocetin (trans-Crocetin) shown to exert strong NMDA receptor affinity and is thought to be responsible for the CNS activity of saffron.Cellular mitochondrial dehydrogenase activity of Caco-2 cells is measured by MTT assay after a 24 h incubation period with the test compounds: Hydroalcoholic saffron extract saffron extract (SE, 0.5-1 mg/mL) and crocin-1 (250-1000 μM) reveal no negative significant changes in cellular viability. Transcrocetin at 10 μM level does not change viability while higher concentrations (40-160 μM) reduces significantly cellular viability.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: trans-Crocetin meglumine | Transcrocetin meglumine salt | Transcrocetin meglumine

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途