化合物 T13256 T13256

Product Introduction
Bioactivity


英文名: UP202-56

描述: UP202-56 is an adenosinergic agonist and is an adenosine analog.

体外活性: UP202-56(oral administration) are assessed on carrageenan-induced spinal c-Fos protein expression and peripheral oedema. Oral UP202-56 (10, 30 or 50 mg/kg) dose-dependently reduces the number of carrageenan-induced c-Fos like immunoreactivity (c-Fos-LI) neurons (r=0.931. P<0.0001), with the highest dose of UP202-56 producing 72±4% reduction of the total number of carrageenan-induced spinal c-Fos-LI neurons, and 12±3% and 33±6% of reduction of control carrageenan oedema at paw and ankle levels, respectively.UP202-56 dose-dependently reduced the expression of spinal cord c-Fos protein in carrageenan inflammatory pain model [1]. UP202-56 is an adenosine agonist[2].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: UP202 56 | UP202-56 | UP-202-56 | UP20256

相关产品: TBPB | Solifenacin | Piperidolate | (S)-Coclaurine | NS3861 | Fesoterodine | Primidone | Disopyramide | AQW051 | Tiotropium bromide

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途