化合物 T13376L T13376L
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
10 mg | T13376L | ¥1,080.00 | 询底价 |
50 mg | T13376L | ¥3,705.00 | 询底价 |
100 mg | T13376L | 面议 | 询底价 |
200 mg | T13376L | 面议 | 询底价 |
Product Introduction
Bioactivity
英文名: YS-49 monohydrate (132836-42-1 free base)
描述: YS-49 (monohydrate) is an activator of PI3K/Akt (a downstream target of RhoA).
体外活性: In RAVSMC and RAW 264.7 cells, YS-49 (1-100?μM; 18 hours; ) concentration-dependently inhibits the accumulation of nitrite in both RAVSMC and RAW 264.7 exposed to lipopolysaccharide (LPS) plus INF-γ, with IC50 values of 22 μM and 30?μM, respectively[2].At the transcriptional level, YS-49 (10-100?μM; 18 hours; RAVSMC and RAW 264.7 cells) suppresses iNOS gene expression induced by LPS and/or cytokines in RAVSMC and RAW 264.7 cells [2].
体内活性: In male Sprague Dawley rats,YS-49 (5?mg/kg; intraperitoneal injection; 8 hours; ) treatment significantly reduces serum NOx levels in LPS-treated rats, the NOx levels reduce from 86 μM to 34 μM[2].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: YS 49 | 132836-42-1 | YS-49 Monohydrate | YS 49 monohydrate (132836 42 1 free base) | YS49 Monohydrate | YS49 | YS-49 | YS49 monohydrate (132836421 free base) | YS 49 Monohydrate | 132836-42-1 free base
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途