4-乙烯基苯酚 T13509

Product Introduction
Bioactivity


英文名: 4-Vinylphenol

描述: 4-Vinylphenol 是酒中乳酸菌对香豆酸和阿魏酸的代谢产物，在白花蛇舌草中发现。 4-Vinylphenol 在体内诱导细胞凋亡。

体外活性: 4-Vinylphenol (100 µg/mL) significantly increases the expressions of caspase 3, likely sensitizing CSC-enriched MDAMB-231 cells to apoptosis. 4-Vinylphenol (50, 100 µg/mL) significantly suppresses cell proliferation in CSC-enriched MDA-MB-231 cells. 4-Vinylphenol (12.5-200 µg/mL) significantly reduces cell viability in parental MDA-MB-231 cells, and the IC50 value is 109 µg/mL. 4-Vinylphenol (0.15, 0.3 µg/mL) reduces sphere‑formation and vimentin expression on CSCs in breast cancer. 4-Vinylphenol significantly reduces ALDH1A1 expression by 50% in CSC-enriched MDA-MB-231 cells[1].

存储条件: store at low temperature,keep away from direct sunlightPowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 145 mg/mL (1206.82 mM)


关键字: tumor | blood | Inhibitor | invasive | Endogenous Metabolite | 4 Vinylphenol | 4-Vinylphenol | formation | vessels | Apoptosis | 4Vinylphenol | inhibit | breast

相关产品: Thioridazine hydrochloride | CCT007093 | Methyl 3,4-dihydroxybenzoate | Enzastaurin | Oleandrin | Pomolic acid | Quisinostat dihydrochloride | Sarsasapogenin | Flavokawain B | NBDHEX

相关库: Anti-Tumor Natural Product Library | Tobacco Monomer Library | Selected Plant-Sourced Compound Library | Bioactive Compounds Library Max | Traditional Chinese Medicine Monomer Library | Natural Product Library for HTS | Food as Medicine Compound Library | RO5 Drug-like Natural Product Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途