化合物Arimoclomol maleate T13554
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 289893-26-1 | ¥2,610.00 | 询底价 |
1 mL | 289893-26-1 | ¥823.00 | 询底价 |
100 mg | 289893-26-1 | ¥5,580.00 | 询底价 |
10 mg | 289893-26-1 | ¥1,220.00 | 询底价 |
50 mg | 289893-26-1 | ¥3,880.00 | 询底价 |
2 mg | 289893-26-1 | ¥443.00 | 询底价 |
1 mg | 289893-26-1 | ¥297.00 | 询底价 |
5 mg | 289893-26-1 | ¥731.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Arimoclomol maleate
描述: Arimoclomol maleate (BRX-220) 是一种热休克蛋白 (HSP) 的共诱导剂。它通过增强 Hsp 表达来保护运动神经元,进而通过蛋白酶体-泛素系统直接影响蛋白质聚集和错误折叠装配体的清除
体内活性: Arimoclomol, administered for 5 d, has a protective effect against CCK-induced acute pancreatitis. Repeated CCK treatment results in the typical laboratory and morphological changes of experimentally induced pancreatitis. The pancreatic levels of HSP60 and HSP72 are significantly increased in the animals treated with Arimoclomol [1]. Arimoclomol is a co-inducer of heat shock proteins for the potential treatment of amyotrophic lateral sclerosis (ALS), the most common form of motor neuron disease [2].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 250 mg/mL (581.60 mM)
关键字: system | neurons | Inhibitor | motor | clearance | Arimoclomol | Arimoclomol maleate | BRX 220 | Heat shock proteins | aggregation | ubiquitin | HSP | misfolded | inhibit | protein | BRX220 | proteasome | Arimoclomol Maleate | assemblies | co-inducer
相关产品: Gedunin | NCT-58 | HSP90-IN-27 | BIIB021 | Debio 0932 | VER-50589 | GRP78-IN-3 | VER-49009 | JG-231 | Falcarinol
相关库: Drug Repurposing Compound Library | Anti-Breast Cancer Compound Library | Anti-Cancer Drug Library | Clinical Compound Library | Anti-Metabolism Disease Compound Library | Anti-Cancer Clinical Compound Library | Cytoskeletal Signaling Pathway Compound Library | Preclinical Compound Library | NO PAINS Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途