化合物 T13560L T13560L

Product Introduction
Bioactivity


英文名: AT-1002 TFA (835872-35-0 free base)

描述: AT-1002 TFA is a tight junction regulator and absorption enhancer. It is a 6-mer synthetic peptide.

体外活性: AT-1002 reversibly increases the paracellular transport of molecules across the epithelial barrier. AT-1002 can undergo Cys-Cys dimerization [1]. Undifferentiated Caco-2 cells are treated with AT-1002 (0 to 5 mg/mL, 3 or 24 hours) and viability is assessed by measuring cellular ATP content. Treatment with AT-1002 for up to 3 h does not affect cell viability at any concentration. In particular, the viability of Caco-2 cells is not affected by 5 mg/mL AT-1002. AT-1002 reduces cell viability after 24 h at concentrations of 2.5 mg/mL and higher. However, the cells remain viable after 24 h if the cells are washed after exposure to AT-1002 for 3 h [2].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: AT1002 TFA (835872350 free base) | 835872-35-0 free base | AT 1002 TFA (835872 35 0 free base) | 835872-35-0

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途