化合物AZ-1355 T13563

Product Introduction
Bioactivity


英文名: AZ-1355

描述: AZ-1355是一种新型二苯并恶西平衍生物，具有降脂效果。

细胞实验: The lipid-lowering profile in rodents AZ-1355, A New Dibenzoxazepine Derivative

动物实验: AZ-1355 (150 mg/kg) reproducibly lowers serum total cholesterol (TC) in the Triton hyperlipidemic mice. AZ-1355 (50 mg/kg) significantly reduces serum TG and the 100 mg/kg dose results in serum TC and TG reduction in rats. AZ-1355 (100 mg/kg) reduces total liver TC in rats fed CE-2, and the 50 mg/kg dose reduces hepatic TC in rats fed the high-fat diet on both bases, and it also reduces the total hepatic TG of the CE-2 fed rats.

体内活性: AZ-1355 (150 mg/kg) reproducibly lowers serum total cholesterol (TC) in the Triton hyperlipidemic mice. AZ-1355 (50 mg/kg) significantly reduces serum TG and the 100 mg/kg dose results in serum TC and TG reduction in rats. AZ-1355 (100 mg/kg) reduces total liver TC in rats fed CE-2, and the 50 mg/kg dose reduces hepatic TC in rats fed the high-fat diet on both bases, and it also reduces the total hepatic TG of the CE-2 fed rats[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 22.5 mg/mL (75.17 mM)


关键字: AZ 1355 | AZ1355 | AZ-1355

相关产品: PF-4693627 | Agnuside | 2-Acetylbenzoic acid | Taraxasterol | Pizuglanstat | Prostaglandin D3 | Neoechinulin A | RO1138452 | CAY10526 | 1,7-Dihydroxy-2,3-methylenedioxyxanthone

相关库: Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途