化合物(S,R,S)-AHPC-Me hydrochloride T13671

Product Introduction
Bioactivity


英文名: (S,R,S)-AHPC-Me hydrochloride

描述: (S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is a chemical compound utilized in the synthesis of ARV-771, an exceptionally potent BET protein degrader. This compound selectively degrades BET protein in cells resistant to castration, exhibiting a remarkable DC50 <1 nM. Recognized as VHL ligand 2 hydrochloride, (S,R,S)-AHPC-Me hydrochloride serves as the VHL ligand derived from (S,R,S)-AHPC for the recruitment of von Hippel-Lindau (VHL) protein.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 62 mg/mL(128.88 mM)


关键字: VHL ligand 2 Hydrochloride | Ligands for E3 Ligase | (S,R,S)AHPCMe hydrochloride | E3 ligase-recruiting Moiety | (S,R,S) AHPC Me hydrochloride | AHPC-Me Hydrochloride | VHL ligand2 | VHL ligand 2 | inhibit | VHL ligand-2 | Inhibitor

相关产品: AR antagonist 1 | (S,R,S)-AHPC-PEG1-N3 | E3 ligase Ligand 23 | VL285 | Pomalidomide-PEG4-Ph-NH2 | (S,R,S)-AHPC-PEG2-N3 | Thalidomide-O-amido-C6-NH2 TFA | Thalidomide-propargyl | (S,R,S)-AHPC-C10-NH2 dihydrochloride | Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride

相关库: NO PAINS Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途