化合物RA190 T13858
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mL | 1617495-03-0 | ¥1,430.00 | 询底价 |
50 mg | 1617495-03-0 | ¥3,590.00 | 询底价 |
100 mg | 1617495-03-0 | ¥5,190.00 | 询底价 |
5 mg | 1617495-03-0 | ¥1,090.00 | 询底价 |
1 mg | 1617495-03-0 | ¥458.00 | 询底价 |
25 mg | 1617495-03-0 | ¥2,420.00 | 询底价 |
10 mg | 1617495-03-0 | ¥1,590.00 | 询底价 |
Product Introduction
Bioactivity
英文名: RA190
描述: RA190 能够与泛素受体 RPN13 的半胱氨酸 88 共价结合,并抑制蛋白酶体功能。
体外活性: Multiple myeloma (MM) lines, even those resistant to bortezomib, are sensitive to RA190 via endoplasmic reticulum stress-related apoptosis. RA190 stabilizes targets of human papillomavirus (HPV) E6 oncoprotein, and preferentially kills HPV-transformed cells.
体内活性: RA190 administration profoundly reduces growth of multiple myeloma and ovarian cancer xenografts, and oral RA190 treatment retards HPV16+ syngeneic mouse tumor growth, without impacting spontaneous HPV-specific CD8+ T cell responses.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 95mg/ml (159.19 Mm)
关键字: RA 190 | inhibit | Proteasome | RA-190 | Inhibitor | RA190
相关产品: Racecadotril | Proteasome-IN-5 | NDMC101 | Z-GGF-CMK | Puromycin aminonucleoside | MG-115 | Alloxan monohydrate | Gemigliptin Tartrate(911637-19-9 free base) | Saxagliptin hydrate | Tripterin
相关库: Anti-Aging Compound Library | HIF-1 Signaling Pathway Compound Library | Bioactive Compounds Library Max | Endoplasmic Reticulum Stress Compound Library | Ubiquitination Compound Library | Inhibitor Library | Hematonosis Compound Library | Autophagy Compound Library | Protease Inhibitor Library | Covalent Inhibitor Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途