醋酸特利加压素 T13920L

Product Introduction
Bioactivity


英文名: Terlipressin Acetate

描述: Terlipressin Acetate 是一种高度选择性的加压素 V1 受体激动剂，对氧和葡萄糖剥夺/再氧合 (OGD/R) 诱导的肠上皮细胞损伤 (IEC-6) 具有抗炎和抗氧化作用，可用于肝肾综合征和耐去甲肾上腺素的败血性休克的研究。

体外活性: Incubation with 25 nM terlipressin significantly improved cell viability, proliferation and apoptosis. Furthermore, terlipressin inhibited the secretion of TNF-α and 15-F2t-isoprostane from IEC-6 cells following OGD/R[1].

体内活性: Using a mouse nonlethal hepatic IR model, we found terlipressin administration significantly ameliorated IR-induced liver apoptosis, necrosis and inflammation[2].

存储条件: keep away from moisturePowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 95mg/mL (70.50mM)


关键字: variceal | hepatorenal | vasoconstriction | Vasopressin Receptor | acute | anti-inflammatory | bleeding | anti-oxidative | Inhibitor | vasopressin | Terlipressin Acetate | Vasoconstrictor | Terlipressin | V1-receptors | inhibit

相关产品: d[Cha4]-AVP acetate(500170-27-4 free base) | Conopressin S acetate(111317-90-9 free base) | Vasopressin Dimer (parallel) (TFA) | Balovaptan | Tolvaptan | Desmopressin acetate (16679-58-6 free base) | Conivaptan hydrochloride | Desmopressin | Mozavaptan | Nelivaptan

相关库: Cyclic Peptide Library | Anti-Cancer Compound Library | Anti-Cancer Drug Library | Membrane Protein-targeted Compound Library | Macrocyclic Compound Library | Peptide Compound Library | Anti-Cancer Clinical Compound Library | Anti-Cancer Approved Drug Library | Preclinical Compound Library | Covalent Inhibitor Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途