头孢妥仑匹酯 T1405
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
100 mg | 117467-28-4 | ¥2,830.00 | 询底价 |
1 mg | 117467-28-4 | ¥157.00 | 询底价 |
50 mg | 117467-28-4 | ¥1,630.00 | 询底价 |
1 mL | 117467-28-4 | ¥583.00 | 询底价 |
500 mg | 117467-28-4 | ¥6,680.00 | 询底价 |
200 mg | 117467-28-4 | ¥4,200.00 | 询底价 |
5 mg | 117467-28-4 | ¥323.00 | 询底价 |
10 mg | 117467-28-4 | ¥583.00 | 询底价 |
25 mg | 117467-28-4 | ¥1,030.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Cefditoren pivoxil
描述: Cefditoren pivoxil (ME 1207) 是一种半合成、广谱、β-内酰胺酶耐药的第三代头孢菌素抗生素,具有杀菌活性。
体外活性: Cefditoren has MIC50/MIC90 results for Moraxella catarrhalis and Haemophilus influenzae of 0.12/0.5 and < or = 0.008/0.015 mg/mL, respectively. [1] Cefditoren (MIC(90), 0.5 mg/mL) is 4- to 128-fold more active than comparison beta-lactams against the pneumoococci and was the most potent beta-lactam (including penicillin) versus beta-haemolytic streptococci. Cefditoren (MIC(90) in mg/mL/% susceptible) activity against all tested H. influenzae (0.03/100) and M. catarrhalis (0.06-0.5/100) is comparable to Cefixime and significantly greater than cefaclor. Cefditoren pharmacokinetics demonstrate a T(1/2) of 1.5-2 hours and C(max) values of 2.8 and 4.6 mg/mL, respectively with 200 or 400 mg doses of Cefditoren pivoxil. [2] Cefditoren possesses a broad-spectrum of cidal antibacterial activity against both Gram-positive and Gram-negative species with stability to many beta-lactamases of clinical importance. [3] Cefditoren is also effective against methicillin-susceptible strains of Staphylococcus aureus. Cefditoren has compared favorably against other orally administered antibiotics used against the most commonly isolated respiratory tract pathogens. [4] Cefditoren up-regulates the expression levels of Mrp2, Bcrp and Oat2, and down-regulate P-gp and Oct1 mRNA expression. [5]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: Ethanol : < 1 mg/mL (insoluble or slightly soluble)
DMSO : 45 mg/mL (72.5 mM)
关键字: Cefditoren pivoxil | ME-1207 | ME1207
相关产品: Sulfapyridine | Continentalic acid | Zoliflodacin | Bavachalcone | Solithromycin | Salinomycin | URB602 | 6-Ethoxychelerythrine | Isepamicin sulfate | Meropenem trihydrate
相关库: Drug Repurposing Compound Library | Approved Drug Library | Antibiotics Library | Drug-induced Liver Injury (DILI) Compound Library | Bioactive Compounds Library Max | Human Metabolite Library | Anti-Bacterial Compound Library | Covalent Inhibitor Library | Nonsteroidal Anti-Inflammatory Compound Library | NO PAINS Compound Library
头孢妥仑匹酯 T1405信息由TargetMol中国为您提供,如您想了解更多关于头孢妥仑匹酯 T1405报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途