化合物 T14088 T14088

Product Introduction
Bioactivity


英文名: ABT-670

描述: ABT-670 is a selective agonist of dopamine D4 receptor. For human D4, ferret D4, and rat D4, the EC50 values are 89 nM, 160 nM, and 93 nM , respectively.

体外活性: ABT-670 is a selective D4 agonist. For human?D4, ferret?D4, and rat?D4, the EC50s values are 89 nM, 160 nM, and 93 nM, respectively[1].

体内活性: ABT-670 (0.1 μmol/kg) robustly induces a high (75%) incidence of erections in male rats. ABT-670 exhibits excellent oral bioavailability in rat, dog, and monkey (68%, 85%, and 91%, respectively) with comparable efficacy, safety, and tolerability[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: ABT670 | ABT 670 | ABT-670

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途