化合物AMG 579 T14217

Product Introduction
Bioactivity


英文名: AMG 579

描述: AMG 579 是一种有效的选择性 PDE10A 抑制剂 (IC50 = 0.1 nM)。

体内活性: AMG 579 statistically reduces PCP-induced behavior in rats within 2 hours. In the PCP-LMA model, the minimum effective dose of AMG 579 was 0.3 mg/kg. AMG 579 has an excellent oral bioavailability of 72% in dogs[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 37.8 mg/mL (85.6 mM)


关键字: AMG 579 | AMG579

相关产品: Drotaverine hydrochloride | Imazodan | Levosimendan | THPP-1 | 2,5-dichloro-4-(difluoromethoxy)-N,N-dimethylbenzene-1-sulfonamide | PQ-10 | CALP2 acetate(261969-04-4 free base) | RS-25344 hydrochloride | Z-HA155 | Fulvic Acid

相关库: Drug Repurposing Compound Library | ReFRAME Related Library | Clinical Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途