化合物 T14374 T14374
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mL | 1034148-15-6 | ¥4,120.00 | 询底价 |
25 mg | 1034148-15-6 | ¥10,600.00 | 询底价 |
50 mg | 1034148-15-6 | ¥13,800.00 | 询底价 |
100 mg | 1034148-15-6 | ¥17,500.00 | 询底价 |
5 mg | 1034148-15-6 | ¥3,730.00 | 询底价 |
Product Introduction
Bioactivity
英文名: AZD2906
描述: AZD2906, a selective glucocorticoid receptor (GR) agonist, demonstrates inhibitory concentrations (IC50s) of 2.2 nM in human GR, 0.3 nM in rat peripheral blood mononuclear cells (PBMC), 41.6 nM in human whole blood, and 7.5 nM in rat whole blood, respectively[1]. Additionally, it induces an increase in micronucleated immature erythrocytes within rat bone marrow.
体外活性: AZD2906 is a selective glucocorticoid receptor (GR), with IC50s of 2.2, 0.3, 41.6 and 7.5 nM at GR in human, rat PBMC and human, rat whole blood, respectively[1].
体内活性: AZD2906 (5, 25, 50 mg/kg, p.o.) increases micronucleated immature erythrocytes (MIE) in the bone marrow of rats after treatment for 2 days[1]. AZD2906 (5, 25 mg/kg, p.o.) induces an accumulation of glycogen in the liver of rats. And it exhibits cortical lymphocytic atrophy of a moderate to marked degree in the thymus of rats[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 125 mg/mL (271.44 mM)
关键字: AZD 2906 | AZD2906 | AZD-2906
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途