化合物AZD5423 T14377

Product Introduction
Bioactivity


英文名: AZD5423

描述: AZD5423 是可吸入的非甾体糖皮质激素受体选择性调节剂，能够有效降改善轻度过敏性哮喘患者的过敏原诱导反应。

体外活性: The affinity of AZD5423 to the glucocorticoid receptor is high with an IC50 of 0.9 nM in a radioligand human glucocorticoid receptor assay. And it selectivity towards other steroid hormone receptors is >900-fold[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 100 mg/mL (205.15 mM)


关键字: AZD5423 | AZD 5423 | AZD-5423 | Inhibitor | Glucocorticoid Receptor | inhibit

相关产品: AZD9977 | Spironolactone | Hydrocortisone 17-butyrate | N-Demethyl Mifepristone | Osilodrostat | Mifepristone | Fludrocortisone acetate | Relacorilant | Dexamethasone Phosphate disodium | Nimodipine

相关库: Drug Repurposing Compound Library | ReFRAME Related Library | Anti-Cancer Drug Library | Clinical Compound Library | Bioactive Compounds Library Max | Anti-Cancer Clinical Compound Library | Nuclear Receptor Compound Library | Endocrinology-Hormone Compound Library | NO PAINS Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途