化合物Eperezolid T15237

Product Introduction
Bioactivity


英文名: Eperezolid

描述: Eperezolid (PNU-100592) 是一种在体外表现出良好抑制活性的恶唑烷酮类抗生素。

体外活性: The specific binding of eperezolid is dose-dependent and is proportional to the ribosome concentrations. The binding of eperezolid to the ribosome is competitively inhibited by chloramphenicol and lincomycin. However, unlike chloramphenicol and lincomycin, eperezolid does not inhibit the puromycin reaction, indicating that the oxazolidinones have no effect on peptidyl transferase [2]. Antibiotic Eperezolid binds specifically to the 50S ribosomal subunit of Escherichia coli. eperezolid was found to bind only to the 50S subunit, with similar affinity as to the 70S ribosome, and to have no affinity for the 30S subunit [3].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 44 mg/mL (111.56 mM)


关键字: Bacterial | Eperezolid | PNU 100592 | Inhibitor | PNU100592 | inhibit | Antibiotic

相关产品: Nifursol | 2-Hydroxy-1-methoxyanthraquinone | Resazurin sodium | Pyrazinamide | Thonzonium Bromide | Nepetoidin B | Ceftiofur | Mezlocillin Sodium | Aureothricin | Demeclocycline hydrochloride

相关库: Antibiotics Library | ReFRAME Related Library | Bioactive Compounds Library Max | Human Metabolite Library | Inhibitor Library | Anti-Bacterial Compound Library | Anti-Infection Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途