化合物gamma-DGG acetate T15369L
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
50 mg | 2935387-13-4 | ¥1,155.00 | 询底价 |
2 mg | 2935387-13-4 | ¥322.00 | 询底价 |
100 mg | 2935387-13-4 | ¥1,827.00 | 询底价 |
10 mg | 2935387-13-4 | ¥637.00 | 询底价 |
200 mg | 2935387-13-4 | ¥2,737.00 | 询底价 |
5 mg | 2935387-13-4 | ¥467.00 | 询底价 |
Product Introduction
Bioactivity
英文名: gamma-DGG acetate(6729-55-1 free base)
描述: gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) 是一种 AMPA 受体的竞争性阻断剂。
体外活性: gamma-DGG (γ-DGG) acetate is the most effective antagonist of the excitatory postsynaptic potentials (e.p.s.p.s). Its action is reversible and not associated with any change in the passive membrane properties of the granule cells or in the apparent reversal potential of the e.p.s.p.gamma-DGG blocks less at higher glutamate concentration. gamma-DGG (200-400 μM) in the bath decreases the miniature EPSC (mEPSC) amplitude by 26±2% (n=5 synapses) and shifts both the mEPSC amplitude distribution and the cumulative probability curve to the left[1]. The quantal analysis displays that the reduction in the e.p.s.p. paralleled the reduction in quantal size rather than quantal content, confirming a post-synaptic site of the action of gamma-DGG[2].
存储条件: keep away from moisturePowder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : Slightly soluble
关键字: gamma-DGG acetate(6729-55-1 free base) | gammaDGG acetate(6729551 free base) | gamma DGG acetate(6729 55 1 free base) | rDGG | gamma-D-Glutamylglycine | gammaDGG | r-D-Glutamylglycine
相关产品: Citric acid trilithium salt tetrahydrate | JNJ-40411813 | SIB-1757 | MFZ 10-7 | ADX88178 | (R)-3,4-DCPG HCl | (S)-3,4-DCPG | TAT-GluA2 3Y acetate(1404188-93-7 free base) | Basimglurant | MPEP
相关库: Anti-Neurodegenerative Disease Compound Library | Neurotransmitter Receptor Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Neuronal Signaling Compound Library | Inhibitor Library | NO PAINS Compound Library | Anti-Alzheimer's Disease Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途