化合物inS3-54A18 T15582
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
500 mg | 328998-53-4 | ¥11,300.00 | 询底价 |
50 mg | 328998-53-4 | ¥3,980.00 | 询底价 |
100 mg | 328998-53-4 | ¥5,630.00 | 询底价 |
1 mg | 328998-53-4 | ¥412.00 | 询底价 |
5 mg | 328998-53-4 | ¥993.00 | 询底价 |
10 mg | 328998-53-4 | ¥1,570.00 | 询底价 |
1 mL | 328998-53-4 | ¥1,090.00 | 询底价 |
25 mg | 328998-53-4 | ¥2,730.00 | 询底价 |
2 mg | 328998-53-4 | ¥598.00 | 询底价 |
Product Introduction
Bioactivity
英文名: inS3-54A18
描述: inS3-54A18 是一种有效的 STAT3 抑制剂。 inS3-54A18 具有抗癌作用。
体外活性: inS3-54A18 inhibits the expression of STAT3 downstream target genes and the binding of STAT3 to its endogenous target sequences. inS3-54A18 (5 μM) decreases wound healing to 64% and 76% for A549 and MDA-MB-231 cells, respectively. inS3-54A18 at 10 μM further reduces the healing to 47% and 39%, respectively. inS3-54A18 does not affect the constitutive or IL-6-induced STAT3 activation but represses the STAT3 target gene (survivin) expression[1].
体内活性: inS3-54A18 (200 mg/kg, p.o.) inhibits tumor growth, metastasis. In a mouse xenograft model of A549 cells, inS3-54A18 (200 mg/kg, p.o.) also inhibits expression of STAT3 target genes[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 150 mg/mL (401.25 mM)
关键字: Inhibitor | inS-3-54A18 | inS3 54A18 | inS3-54A18 | inS354A18 | inhibit | STAT
相关产品: Garcinone C | Eupalinolide I | FLLL32 | CMD178 TFA | Fludarabine | STAT5-IN-2 | JAK-STAT-IN-1 | MNK8 | Ganoderic acid B | Stafib-2
相关库: Anti-Prostate Cancer Compound Library | Anti-Liver Cancer Compound Library | Transcription Factor-Targeted Compound Library | Anti-Cancer Metabolism Compound Library | Anti-Cancer Compound Library | Anti-Lung Cancer Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Anti-Cancer Active Compound Library | Anti-Pancreatic Cancer Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途