化合物 T15825 T15825
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
100 mg | 107889-32-7 | ¥17,500.00 | 询底价 |
25 mg | 107889-32-7 | ¥10,600.00 | 询底价 |
50 mg | 107889-32-7 | ¥13,800.00 | 询底价 |
Product Introduction
Bioactivity
英文名: LY 178002
描述: LY 178002 is an effective inhibitor of 5-lipoxygenase (5-LPO), phospholipase A2 (IC50: 0.6 μM for 5-lipoxygenase). LY 178002 also inhibits cellular production of LTB4 by human polymorphonuclear leukocytes and displays relatively weak inhibition on cyclooxygenase.
体外活性: LY178002 suppresses the generation of LTB4, PLA2 and FCO (IC50s of 0.1, 6.3 and 4.2 μM) .
体内活性: LY 178002 (50 mg/kg) inhibits soft tissue swelling in the uninjected paw by 81% and inhibits bone damage in rats. LY178002 (50 mg/kg; p.o.) inhibits the uninjected paw swelling by 75%, in the established FCA model. The minimum effective dose for LY178002 is 10 mg/kg p.o.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: LY178002 | LY-178002 | LY 178002
相关产品: AGN 192870 | ER 50891 | Fenretinide | MM 11253 | BMS641 | Bexarotene | K-8012 | Magnolol | Isotretinoin | Etodolac
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途