甲喋呤杂质E T16045
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
50 mg | 19741-14-1 | ¥1,330.00 | 询底价 |
25 mg | 19741-14-1 | ¥828.00 | 询底价 |
500 mg | 19741-14-1 | ¥4,590.00 | 询底价 |
100 mg | 19741-14-1 | ¥1,970.00 | 询底价 |
5 mg | 19741-14-1 | ¥257.00 | 询底价 |
200 mg | 19741-14-1 | ¥2,930.00 | 询底价 |
10 mg | 19741-14-1 | ¥398.00 | 询底价 |
1 mL | 19741-14-1 | ¥359.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Methotrexate metabolite
描述: Methotrexate metabolite (DAMPA) (DAMPA)是 Methotrexate 的活性代谢物。Methotrexate 具有拮抗叶酸 (folic acid) 的作用,被用作免疫抑制剂。
体外活性: Methotrexate metabolite was the most active, with 50% inhibitory concentrations in vitro of 446 ng/ml against the antifolate-sensitive strain and 812 ng/ml against the highly resistant strain under physiological folate conditions. Methotrexate metabolite potentiates the activity of the sulfone dapsone, an inhibitor of dihydropteroate synthase, but not that of chlorcycloguanil, a known inhibitor of dihydrofolate reductase (DHFR)[2].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 4 mg/mL (12.30 mM)
关键字: Inhibitor | Antifolate | Drug Metabolite | inhibit | Methotrexate metabolite
相关产品: Pyrimethamine | Methotrexate | Pemetrexed | Metoprine | WR99210 | Trimethoprim | Pemetrexed disodium hemipenta hydrate | Folinic acid | Farletuzumab | Folinic acid calcium
相关库: Anti-Cancer Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Anti-Parasitic Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途