化合物NBD-556 T16276

Product Introduction
Bioactivity


英文名: NBD-556

描述: NBD-556是一种 CD4 模拟物，识别 HIV-1 包膜蛋白 gp120 并诱导 gp120 重组，类似于 CD4 结合，可阻断 gp120-CD4 的相互作用。

体外活性: HIV NBD-556 N-phenyl-N′-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamide analogs as a novel class of human immunodeficiency virus type 1 (HIV-1) entry inhibitors that block the gp120–CD4 interaction. The small molecule NBD-556 mimics CD4 by binding the gp120 exterior envelope glycoprotein, moderately inhibiting virus entry into CD4-expressing target cells, and enhancing CCR5 binding and virus entry into CCR5-expressing cells lacking CD4.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: H2O : < 0.1 mg/mL (insoluble)
DMSO : 33.33 mg/mL (98.66 mM)


关键字: inhibit | HIV-1 | fusion | virus-cell | Human immunodeficiency virus | HIV | NBD 556 | Inhibitor | NBD556 | gp120 | CD4 | NBD-556 | mimetic

相关产品: Azulene | Zalcitabine | DAPTA | MK-2048 | (+)-Nortrachelogenin | Zingibroside R1 | Ganodermanondiol | Isosinensetin | Plerixafor | Cys-TAT(47-57) acetate(583836-55-9 Free base)

相关库: ReFRAME Related Library | Bioactive Compounds Library Max | PPI Inhibitor Library | NO PAINS Compound Library | Anti-Viral Compound Library | Bioactive Compound Library | Anti-Infection Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途