印苦楝内酯 T16324

Product Introduction
Bioactivity


英文名: Nimbolide

描述: Nimbolide 是源自印楝叶和花的一种三萜。它抑制CDK4/CDK6激酶活性。它抑制 NF-κB，Wnt，PI3K-Akt，MAPK 和 JAK-STAT 信号通路。它通过抑制NF-κB 而诱导肿瘤细胞凋亡。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 60 mg/ml (128.61 mM)


关键字: CDK | Apoptosis | Nuclear factor-kappaB | inhibit | NF-κB | Nuclear factor-κB | Nimbolide | Inhibitor | Cyclin dependent kinase

相关产品: Demethylzeylasteral | Rebastinib | RUNX-IN-2 | Eriocalyxin B | 3BDO | Degrasyn | Delanzomib | CHIR-124 | INCB-057643 | Betulin

相关库: Antioxidant Compound Library | Anti-Breast Cancer Compound Library | Anti-Cancer Compound Library | Kinase Inhibitor Library | Inhibitor Library | Natural Product Library for HTS | Apoptosis Compound Library | NO PAINS Compound Library | Covalent Inhibitor Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途