磷酸咯萘啶 T16697
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
5 mg | 76748-86-2 | ¥147.00 | 询底价 |
25 mg | 76748-86-2 | 面议 | 询底价 |
10 mg | 76748-86-2 | ¥196.00 | 询底价 |
1 mL | 76748-86-2 | ¥347.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Pyronaridine tetraphosphate
描述: Pyronaridine tetraphosphate 是一种具有口服活性的、含甘露醇的DNA 拓扑异构酶 2 的抑制剂和红细胞裂殖杀灭剂,具有抗疟活性和抗肿瘤活性。Pyronaridine tetraphosphate 可治疗 P. falciparum 和 Echinococcus granulosus感染,可减轻埃博拉病毒传播。
体外活性: With an IC50 value of 1.53-3.94 nM, pyronaridine tetraphosphate (24 h) exhibits anti-P. falciparum activity[2].
体内活性: Reducing the parasitic burden in Echinococcus granulosus-infected mice, pyronaridine tetraphosphate (57 mg/kg, oral administration, q.d. for 30 days) has been demonstrated[1].Reducing the parasitic burden in secondarily infected (cysts) mice, pyronaridine tetraphosphate (57 mg/kg, intraperitoneal injection, q.d. for 3 days) has shown efficacy[1].Exhibiting a higher exposure in the liver than in the plasma in male ICR mice, pyronaridine tetraphosphate (57 mg/kg, intraperitoneal injection, for a single dose) has been observed[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: H2O : 20 mg/mL (21.98 mM)
DMSO : 10 mg/mL (10.99 mM)
关键字: Pyronaridine | Pyronaridine tetraphosphate
相关产品: CPT-Se3 | Daunorubicin hydrochloride | Cardioxane | 9-amino-CPT | Ganoderic acid X | Gatifloxacin | Enoxacin hydrate | Topoisomerase II inhibitor 16 | 3',5,5',7-Tetrahydroxy-4',6-dimethoxyflavone | Eleutherin
相关库: Drug Repurposing Compound Library | Inhibitor Library | Anti-Parasitic Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途